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Creatinine and Muscle Breakdown Creatinine is an byproduct of the creatine enzyme acting in the body. Creatine breaks down proteins. As a result, Creatinine is often used as an indicator in research studies having to do with muscle breakdown in exercise. It can be measured in blood but also in urine with the help of a creatinine assay. There has been controversy about athletic beverage maker Accelerade's claims that protein ingested prior to strenuous endurance exercise reduces muscle breakdown. Gatorade Sports Science Institute (GSSI) maintains that protein provides no added benefit. In a timed research study done by Dr. Michael Saunders et al, protein did have a positive benefit, however in a time-trial study done by Dr. Martin Gibala et al, no benefit was perceived.

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Gatorade Sports Science Institute | Accelerade

Contributed by kaje on March 2, 2008, at 4:50 PM UTC.

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